In 1893 Myers wrote a small collection of essays, Science and a Future Life. In 1903, after Myers's death, Human Personality and Its Survival of Bodily Death was compiled and published. This work comprises two large volumes at 1,360 pages in length and presents an overview of Myers's research into the unconscious mind. Myers believed that a theory of consciousness must be part of a unified model of mind which derives from the full range of human experience, including not only normal psychological phenomena but also a wide variety of abnormal and "supernormal" phenomena. In the book, Myers believed he had provided evidence for the existence of the soul and survival of personality after death. The book cites cases of automatic writing, hypnotism, mediumship, possession, psychokinesis, and telepathy.

In Human Personality and Its Survival of Bodily Death, Myers speculated on the existence of a deep region of the unconscious (collective unconscious) or what he termed the “subliminal self”, which he believed could account for paranormal events. He also proposed the existence of a “metetherial world,” a world of images lying beyond the physical world. He wrote that apparitions are not hallucinations but have a real existence in the metetherial world which he described as a dream-like world. Myers’ belief that apparitions occupied regions of physical space and had an objective existence was in opposition to the views of his co-authors Gurney and Podmore who wrote apparitions were telepathic hallucinations.

It was well received by parapsychologists and spiritualists, being described as "the Bible of British psychical researchers". Théodore Flournoy and William James both positively reviewed the book.