My local printer says that printing in small quantities means per copy cost is very high. So what does that mean if you are printing one copy at a time?
The printer you have spoken to is talking about offset printing. Offset printing has high setup costs. Hence, if you print small number of copies, the per copy cost is very high. But becomes reasonable as the number of copies goes up.
When we print one copy at a time, we use a different printing technology called print-on-demand (POD). The per copy cost here is higher than what you would get if you printed large number of copies with offset printing. But it is still much more reasonable. While printing one copy is infeasible with offset printing, with print on demand it is within the range of feasibility.